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INHANCE is an international consortium of scientists involved
in research on head and neck cancer, comprising oral cavity,
pharynx, and larynx. Although originally organized among principal
investigators of epidemiological case-control studies of head
and neck cancer, INHANCE is open to researchers from other disciplines
relevant to head and neck cancer research, and to investigators
involved in other types of epidemiological studies (e.g., cohort
and family-based studies). The eligibility criteria for INHANCE
membership is shown below.
INHANCE members are epidemiologists involved in head and neck
cancer studies and scientists with expertise in domains relevant
to head and neck research. Members are expected to bring to
the consortium their expertise, ideas and resources, including
results, raw data and biological samples. Membership is effective
upon notification to and confirmation of acceptance by the executive
committee. Active participation in at least one working group
is a requirement for maintaining membership.
If you would like more information on becoming a member, please
contact:
Mia Hashibe, Ph.D.
Division of Public Health
Department of Family & Preventive Medicine
University of Utah School of Medicine
375 Chipeta Way, Suite A
Salt Lake City, UT, 84108
Email:
Eligibility criteria for joining the INHANCE Consortium
(drafted by the INHANCE Executive Committee):
Studies are eligible for inclusion in INHANCE if they have
the potential to contribute to research on causes, mechanisms
and prevention of head and neck cancer within the framework
of collaborative projects carried out in the consortium. Studies
should be methodologically sound and contribute good-quality
data and biological samples. Studies considered for inclusion
are MAINLY molecular and genetic epidemiological studies (typically
of case-control or cohort design, including both information
on exposure to risk factors FROM QUESTIONNAIRES OR SIMILAR SOURCES
and biological samples), BUT well-conducted clinical series
from understudied populations, and large-scale CASE-SERIES and
epidemiological studies without biological samples can be also
considered for inclusion. The decision on inclusion in the consortium
is taken by the Executive Committee, preferably by consensus.
The following aspects are considered by the Executive Committee:
- type and quality of information on exposure to risk factors
and potential confounders;
- type and quality of results of biological measurements;
- type, amount and quality of biological samples available
for further analyses (blood, tumour, normal H&N, other);
- protection from bias;
- information on clinical aspects (e.g., treatment) and outcome;
- sample size (number of cases);
- uniqueness of study population, e.g., in terms of exposure
or genetic background.
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